Rapid Integration of Multi-copy Transgenes Using Optogenetic Mutagenesis in Caenorhabditis elegans
Stably transmitted transgenes are indispensable for labeling cellular components and manipulating cellular functions.In NATURAL Caenorhabditis elegans, transgenes are generally generated as inheritable multi-copy extrachromosomal arrays, which can be stabilized in the genome through a mutagenesis-mediated integration process.Standard methods to int